John B Porter Selected Research

Tablets

1/2019	Predicting serum ferritin levels in patients with iron overload treated with the film-coated tablet of deferasirox during the ECLIPSE study.
11/2018	Patient-reported outcomes from a randomized phase II study of the deferasirox film-coated tablet in patients with transfusion-dependent anemias.
5/2017	New film-coated tablet formulation of deferasirox is well tolerated in patients with thalassemia or lower-risk MDS: Results of the randomized, phase II ECLIPSE study.

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John B Porter Research Topics

Disease

52	Iron Overload 02/2024 - 06/2002
30	Thalassemia 10/2023 - 12/2007
24	beta-Thalassemia (Cooley's Anemia) 01/2023 - 07/2004
12	Anemia 02/2024 - 09/2007
9	Heart Failure 01/2023 - 06/2002
9	Siderosis 03/2017 - 03/2010
9	Sickle Cell Anemia (Hemoglobin S Disease) 01/2016 - 09/2007
8	Cardiomyopathies (Cardiomyopathy) 03/2017 - 11/2004
6	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2023 - 12/2007
5	Hemolysis 02/2024 - 01/2009
5	Fibrosis (Cirrhosis) 03/2017 - 06/2003
4	Stroke (Strokes) 03/2017 - 03/2011
3	Inflammation (Inflammations) 03/2020 - 01/2009
2	Inborn Genetic Diseases (Disease, Hereditary) 02/2024 - 03/2020
2	Hemolytic Anemia 02/2024 - 10/2011
2	Hepatocellular Carcinoma (Hepatoma) 05/2020 - 01/2009
2	Exanthema (Rash) 01/2017 - 01/2011
2	Polycythemia (Erythrocytosis) 01/2016 - 01/2012
2	Pulmonary Hypertension 09/2013 - 04/2010
2	Hemochromatosis (Bronze Diabetes) 07/2013 - 03/2013
2	Aplastic Anemia (Anemia, Hypoplastic) 07/2013 - 10/2010
1	Pyruvate Kinase Deficiency of Red Cells 02/2024
1	Polycythemia Vera 01/2023
1	Neoplasms (Cancer) 01/2023
1	Arthralgia (Joint Pain) 10/2022
1	Pain (Aches) 10/2022
1	Headache (Headaches) 10/2022
1	Neuroblastoma 05/2020
1	Liver Diseases (Liver Disease) 03/2020
1	Necrosis 01/2020
1	Insulinoma 05/2019
1	Hemosiderosis 10/2017
1	Disease Progression 01/2017
1	Tics (Tic) 08/2016
1	Carcinogenesis 03/2016

Drug/Important Bio-Agent (IBA)

68	IronIBA 10/2023 - 06/2002
28	Deferasirox FDA Link 01/2019 - 10/2006
13	Ferritins (Ferritin)IBA 10/2023 - 12/2009
13	Deferoxamine (Desferal)FDA LinkGeneric 01/2016 - 11/2004
12	Chelating AgentsIBA 05/2019 - 10/2006
11	Transferrin (beta 2 Transferrin)IBA 10/2023 - 06/2005
6	DeferiproneIBA 01/2016 - 06/2003
4	HepcidinsIBA 01/2017 - 01/2009
3	luspaterceptIBA 10/2023 - 10/2022
3	TabletsIBA 01/2019 - 05/2017
3	Growth Differentiation Factor 15IBA 01/2017 - 01/2009
3	Biomarkers (Surrogate Marker)IBA 01/2017 - 10/2011
2	Free RadicalsIBA 05/2020 - 05/2019
2	TeaIBA 01/2020 - 05/2019
2	Hemoglobins (Hemoglobin)IBA 01/2018 - 01/2016
2	hemoglobin LutonIBA 01/2016 - 01/2012
2	Oxygen (Dioxygen)IBA 01/2016 - 01/2012
2	Isoflurophate (DFP)FDA Link 05/2013 - 10/2011
2	4,5- dihydro- 2- (2- hydroxy- 3- (3,6,9- trioxadecyloxy)phenyl)- 4- methyl- 4- thiazolecarboxylic acidIBA 04/2012 - 04/2011
2	CreatinineIBA 07/2011 - 01/2011
2	Alanine Transaminase (SGPT)IBA 01/2011 - 09/2008
1	Pyruvate KinaseIBA 02/2024
1	mitapivatIBA 02/2024
1	Heme (Haem)IBA 10/2023
1	CarbohydratesIBA 01/2023
1	Small Interfering RNA (siRNA)IBA 01/2023
1	AcetylgalactosamineIBA 01/2023
1	betibeglogene autotemcelIBA 01/2022
1	GlobinsIBA 01/2022
1	Fatty Acids (Saturated Fatty Acids)IBA 05/2020
1	LipidsIBA 05/2020
1	Familial apoceruloplasmin deficiencyIBA 03/2020
1	Ceruloplasmin (Ferroxidase)IBA 03/2020
1	NitrogenIBA 01/2020
1	CurcuminIBA 01/2020
1	Urea (Carbamide)FDA LinkGeneric 01/2020
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2020
1	Interleukin-6 (Interleukin 6)IBA 01/2020
1	Bovine Serum AlbuminIBA 05/2019
1	Insulin (Novolin)FDA Link 05/2019
1	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 05/2019
1	ferric ammonium citrate FDA Link 05/2019
1	apotransferrinIBA 10/2017
1	CollagenIBA 03/2017
1	C.I. direct red 80IBA 03/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2016
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2016
1	ChromiumIBA 01/2016
1	CobaltIBA 01/2016
1	Arginine (L-Arginine)FDA Link 06/2015
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 06/2015
1	Hemoglobin EIBA 01/2015
1	Transferrin Receptors (Transferrin Receptor)IBA 12/2014
1	Erythropoietin FDA Link 12/2014

Therapy/Procedure

24	Chelation Therapy (Therapy, Chelation) 01/2020 - 07/2004
9	Therapeutics 01/2017 - 09/2008
5	Blood Transfusion (Blood Transfusions) 01/2018 - 11/2011
3	Splenectomy 01/2017 - 10/2011
2	Erythrocyte Transfusion 07/2023 - 03/2016
2	Transplantation 03/2017 - 04/2011
2	Heart Transplantation (Grafting, Heart) 03/2017 - 08/2014
2	Hematopoietic Stem Cell Transplantation 01/2017 - 03/2016
1	Drug Therapy (Chemotherapy) 02/2024
1	Stem Cell Transplantation 01/2017
1	Hip Prosthesis 01/2016